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Platelet-RBC Complexes Associated with RBC Clearance
Platelet-RBC (P-RBC) complexes are associated with several diseases such as sickle cell disease, malaria, and immune thrombocytopenia. Since diseased RBCs exhibit similar morphology to aged and...
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Strategies for Blood Deserts
Every country in sub-Saharan Africa and South Asia, along with some other low-income and middle-income countries often experience blood shortages. According to the World Health Organization (WHO),...
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Whole Blood Transfusions Early Improve Survival for Trauma Patients
The balance of transfused blood components for trauma patients has been investigated with an emphasis on including whole blood (WB) to supplement massive transfusion protocols. One recent study found...
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National Surveillance for Unknown Transfusion-Transmitted Infections
The prevention of transfusion-transmitted infections (TTI) is largely based on recruiting donors at low risk of being infected with a TTI and using screening assays to identify known pathogens....
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Recombinant Erythropoietin for Patients with Autoimmune Hemolytic Anemia
Autoimmune hemolytic anemia (AIHA) is a rare disorder with multiple etiologies and usually presents as anemia with hemolysis. Initial treatments for AIHA include steroids and rituximab, but many...
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Stored RBCs May Have Slower Oxygen Unloading for Tissue
Oxygen delivery to tissues is dependent on blood flow, the oxygen carrying capacity of the RBCs (related to hemoglobin levels), and the oxygen saturation of the hemoglobin in a perfusion-limited...
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Motivators and Barriers to Donating Blood Among African Americans
In the U.S., blood donations rates are lower among African Americans than the general population. The National Heart, Lung, and Blood Institute (NHLBI) recently investigated motivators and barriers...
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Transfusion Patterns After CAR T-Cell Therapy for Large B-Cell Lymphoma
Three different types of chimeric antigen receptor (CAR) T-cell therapies have been approved to treat refractory or relapsed large B-cell lymphoma. Many patients have side effects such as immune...
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Blood Donation is Not Associated with Migraine Relief
Migraines are the second leading cause of disability in adults worldwide affecting approximately one billion individuals each year. The effectiveness of conventional migraine therapies, however,...
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Increasing Data Available for Plasma Transfusion Indications
Plasma transfusions are often used to prevent and/or treat bleeding and to control blood volume in patients with trauma or undergoing surgery. Plasma has many other uses including for burn...
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